Paparan Asap Rokok terhadap Sindrom Mata Kering Pada Mahasiswa UPN “Veteran” Jakarta

Authors

  • Kristin Simanjuntak Departemen Biokimia Fakultas Kedokteran Universitas Pembangunan Nasional “Veteran” Jakarta
  • Devi Handayani Putri Departemen Mata Fakultas Kedokteran Universitas Pembangunan Nasional “Veteran” Jakarta
  • Nurina Mutia Farah Fakultas Kedokteran Universitas Pembangunan Nasional “Veteran” Jakarta

DOI:

https://doi.org/10.30736/4ijev.v4iss1.133

Abstract

Asap rokok menghasilkan radikal bebas yang menginduksi stres oksidatif sel sebagai penyebab penyakit. Paparan asap rokok yang terpapar secara terus menerus dalam tubuh berhubungan dengan kerusakan jaringan epitel mata akibat peroksidasi lipid, membentuk hiperosmolaritas air mata menjadi sindrom mata kering. Tujuan penelitian ini untuk mengetahui paparan asap rokok terhadap sindrom mata kering pada mahasiswa UPN“Veteran†Jakarta. Penelitian ini adalah analitik observasional dengan desain cross sectional, sampel mahasiswa UPN “Veteran†Jakarta sebanyak 70 mahasiswa, usia 18-24 tahun diambil secara stratified propotional random sampling. Pengambilan data dilakukan menggunakan kuesioner OSDI, serta menilai kekeringan mata menggunakan uji Schirmer. Hasilnya, frekuensi mahasiswa UPN “Veteran†Jakarta yang merokok masih kategori derajat ringan 80 %, lama merokok 5 tahun dan derajat sedang 20 %, lama merokok 6 tahun, Uji Chi-Square menunjukkan bahwa paparan asap rokok dapat menimbulkan sindrom mata kering (p = 0,003)[L1] , Menghindari asap rokok dan faktor resiko lainnya dapat menurunkan sindrom mata kering, dan diperlukan vitamin A untuk memperbaiki mata kering.

 

Downloads

Download data is not yet available.

References

WHO, Tobacco, 2017

Tirtosastro, S, Murdiyati, AS. Kandungan Kimia Tembakau dan Rokok 2010 ; 2 (2) : 33-43

Calonge, M, Pinto FJ, Gonzalez-Garcia, MJ, Enriquez S, Rosa, ALdl, F I, Lopez MA. Effects of the External Environment on Dry Eye Disease. International Opthalmology Clinic 2017 ; 57 (2) : 23-40

Eva, PR, Whitcher, JP, Vaughan, Asbury. Oftalmologi umum. 2015 ; 17 : 21-34

Ilyas, S, Yulianti SR. Ilmu Penyakit Mata 2015 ; 5 : 51-70

Javadi, MA, Feizi, S. Dry Eye Syndrome. Journal of Ophthalmic and Vision Research 2011 ; l 6 : 192-198

Tiwari, S, Ali, MJ, Vemuganti, GK. Human lacrimal gland regeneration ; perspectives and review of literature. Saudy Journal of Ophthalmology 2014 ; 28 : 12-18

Thomas, J, Jacob, GP, Lekha, A. The Effect of Smoking on the Ocular Surface and The Precorneal Tear Film. Australian Medical Journal 2012 ; 5 (6) : 221-226

Uchino, Y, et.al. Impact of Cigarette Smoking on tear function and forrelation between conjunctival goblet cell and tear concentration in office Worker. Scientific Reports 2016 ; 9 (10) : 15-18

Yamada, M, Mizuno, Y, Shigeyasu, C. Impact Of Dry Eye On Work Productivity. ClinicoRconomics and Putcomes Research 2012 ; 4 :.307-312

Yoon, KC, Song, BY, Seo, MS. Effect of Smoking on tear film and ocular surface. Korean Journal of Ophthalmology 2015 ; 19 : 18-22

Banerjee1.S, Jyotirmoy G, Parames CS, Drug Metabolism and Oxidative Stress: Cellular Mechanism and New Therapeutic Insights. J. Biochem Anal Biochem 2016 ; 5 (1) : 100

Birben E, et.al. Rev. Oxidative Stress and Antioxidant Defense, J World Allergy Organization 2012 ;

Kuo Y-K, Lin I-C, Chien L-N, Lin T-Y, How Y-T, Chen K-H, et al. Dry Eye Disease: A Review of Epidemiology in Taiwan, and its Clinical Treatment and Merits. J Clin Med. 2019 ; 8(8) : 1227.

Xu L, Zhang W, Zhu XY, Suo T, Fun XQ, Fu Y. Smoking and the risk of dry eye: A meta-analysis. Int J Ophthalmol. 2016 ; 9 (10): 1480–6.

Mantelli F, Massaro-Giardano M, Macchi I, Lambiasa A, Bonini A. The cellular mechanism of dry eye ; from phatogenesis to treatment. J Cell Physiol 2013 ; 228 (12) : 2253-2256

Lee SY, Petznick A, Tony L. Associations of systemic diseases, smoking and contact lens wear with severity of dry eye. Ophthalmic physiol Opt 2012 ; 32 (6) : 518 - 526

Sayin N, Kara N, Peku G, Altinkaynak H, Effects of chrome smoking on central corneal thickness, endothelial cell, and dry eye parameters. Cutan Ocul Toxicol 2014 ; 33 (3) : 201-205

Zeev MS Ben, Miller DD, Latkany R. Diagnosis of dry eye disease and emerging technologies. Clin Ophthalmol. 2014 ; 8 : 581–90.

Stern ME, Schaumburg CS, Pflugfelder SC. Dry eye as a mucosal autoimmune disease. Int Rev Immunol. 2013 ; 32 (1) :19–41.

Castro JS , Selegatto IB, Castro RS, Miranda ECM, Vasconcelos JPC, Carvalho KM, et al. Prevalence and risk factors of self reported dry eye in Brazil. Sci Rep 2018 ; 8 (1) : 2–10.

Law SM, Lu X, Yu F, Tseng V, Law SK, Coleman AL. Cigarette smoking and glaucoma in the United States population. Eye. 2018 ; 32 (4) :716–25.

Scott, GA, Catania, LJ, Larkin, KM, Melton, R, Semes, LP, Shovlin, JP. Care of the Patient with Ocular Surface Disorders. American optometric 2011

Friedman, NJ. Impact of dry eye disease and treatment on quality of life. Current opinion in opghthalmology 2010 ; 21(4) : 310-316.

Hosaka, E, Kawamorita, T, Ogasawara, Y, Nakayama, N, Uozato, H, Shimizu, K, Dogru, M, Tsubota, K, Goto, E. Interferometry in the evaluation ofprecorneal tear film thickness in dry eye. American journal of ophthalmology 2011 ; 151 : 18-23

Dahlan, S, Statistik untuk kedokteran dan kesehatan deskriptif, bivariat, dan multivariate 2014 ; 6

PlumX Metrics

Published

2020-03-16

How to Cite

Simanjuntak, K., Putri, D. H., & Farah, N. M. (2020). Paparan Asap Rokok terhadap Sindrom Mata Kering Pada Mahasiswa UPN “Veteran” Jakarta. Jurnal EnviScience (Environment Science), 4(1), 23–30. https://doi.org/10.30736/4ijev.v4iss1.133